HOW DO I OPEN THE SECOND SAFE?
"Basil," whoever that is, has left a helpful hint for his accomplice (we assume).
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While we might not know about their "ultimate target" (yet?), there's another helpful hint in the note.
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What keeps you up all night? Worries? Sure. But there's something else too.
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Something that's already been helpful once.
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And which you are still carrying around, for whatever reason.
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Look at the bag of coffee beans for something that would make a good six-digit code.
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Enter DEBEST, or 332378 on the safe keypad, and turn the handle to open it.